PF4 CLIA Kit for Human(Homo sapiens) | EIAab.comPF4 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > PF4(Gene name) > Human

PF4 (Gene name),

Platelet factor 4 (Protein name ), PLF4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PF4(CXCL4;SCYB4);

Protein name:

Platelet factor 4(PF-4);

Alternative:

Iroplact;C-X-C motif chemokine 4;Oncostatin-A;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotetramer.

Function:

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

101

Sequence:

50:

100:

101:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:5196

MIM:

173460

UniGene:

Hs.81564

String:

P02776

STRING:

9606.ENSP00000296029

Pfam:

PF00048

SMR:

P02776

Uniprot:

P02776

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ELISA Kit for Human PF-4

Cat.:

E0172r

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Packing:

96T

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ELISA Kit for Human PF-4

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ELISA Kit for Human PF-4

Cat.:

E0172h

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Packing:

96T

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ELISA Kit for Human PF-4

Cat.:

E0172m

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Looking for manual.

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Packing:

96T

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ELISA Kit for Human PF-4

Cat.:

E0172p

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Packing:

96T

ELISA Kit for Human PF-4

Cat.:

E0172b

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Packing:

96T

CLIA Kit for Human PF-4

Cat.:

U0172h

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MSDS:

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Packing:

96T

CLIA Kit for Human PF-4

MSDS:

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CLIA Kit for Human PF-4

Cat.:

U0172m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human PF-4

Cat.:

U0172b

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MSDS:

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Packing:

96T

CLIA Kit for Human PF-4

Cat.:

U0172p

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MSDS:

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Packing:

96T

CLIA Kit for Human PF-4

Cat.:

U0172r

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Packing:

96T

Polyclonal Antibody for Human PF-4

Cat.:

P0172Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human PF-4

Cat.:

P0172Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human PF-4

Cat.:

P0172Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human PF-4

Monoclonal Antibody for Human PF-4

Protein for Human PF-4

Cat.:

R0172r

Price:

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Packing:

1mg

Purity:

>90%

Protein for Human PF-4

R&D Technical Data

12% SDS-PAGE analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and characterization of platelet factor 4 cDNA derived from a human erythroleukemic cell line."
Poncz M. , Surrey S. , Larocco P. , Weiss M.J. , Rappaport E.F. , Conway T.M. , Schwartz E.
Blood69:219-223(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Structural and functional comparison of the genes for human platelet factor 4 and PF4alt."
Eisman R. , Surrey S. , Ramachandran B. , Schwartz E. , Poncz M.
Blood76:336-344(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus."
Zhang C. , Thornton M.A. , Kowalska M.A. , Sachis B.S. , Feldman M. , Poncz M. , McKenzie S.E. , Reilly M.P.
Blood98:610-617(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.

"Isolation, crystallization, and primary amino acid sequence of human platelet factor 4."
Hermodson M. , Schmer G. , Kurachi K.
J. Biol. Chem.252:6276-6279(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-101
8.

"Amino acid sequence of human platelet factor 4."
Deuel T.F. , Keim P.S. , Farmer M. , Heinrikson R.L.
Proc. Natl. Acad. Sci. U.S.A.74:2256-2258(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-101
9.

"Primary structure of human platelet factor 4."
Walz D.A. , Wu V.Y. , de Lamo R. , Dene H. , McCoy L.E.
Thromb. Res.11:893-898(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-101
10.

"Complete covalent structure of human platelet factor 4."
Morgan F.J. , Begg G.S. , Chesterman C.N.
Thromb. Haemost.42:1652-1660(1980) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-101
11.

"A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4."
Gupta S.K. , Hassel T. , Singh J.P.
Proc. Natl. Acad. Sci. U.S.A.92:7799-7803(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-101;N-TERMINAL CLEAVAGE;FUNCTION;MASS SPECTROMETRY
tissue: Leukocyte.
12.

"Alternative C-terminal helix orientation alters chemokine function: Structure of the Anti-angiogenic Chemokine, CXCL4L1."
Kuo J.H. , Chen Y.P. , Liu J.S. , Dubrac A. , Quemener C. , Prats H. , Bikfalvi A. , Wu W.G. , Sue S.C.
J. Biol. Chem.288:13522-13533(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HEPARIN-BINDING REGION
13.

"Crystal structure of recombinant human platelet factor 4."
Zhang X. , Chen L. , Bancroft D.P. , Lai C.K. , Maione T.E.
Biochemistry33:8361-8366(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS);SUBUNIT;DISULFIDE BONDS
14.

"NMR solution structure of the 32-kDa platelet factor 4 ELR-motif N-terminal chimera: a symmetric tetramer."
Mayo K.H. , Roongta V. , Ilyina E. , Milius R. , Barker S. , Quinlan C. , La Rosa G. , Daly T.J.
Biochemistry34:11399-11409(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 43-101;SUBUNIT;DISULFIDE BONDS

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